Selected PanTHERA Publications

  1. Investigating the Solubility and Activity of a Novel Class of Ice Recrystallization Inhibitors
    Ampaw A.A.; Newell, K.; Ben, R.N. Investigating the Solubility and Activity of a Novel Class of Ice Recrystallization Inhibitors. Processes 9: 1781-1791 (2021).
  1. The efficacy of ice recrystallization inhibitors in rat lung cryopreservation using a low-cost technique for ex vivo subnormothermic lung perfusion.
    Lautner, L., Himmata, S., Acker, J.P. and Nagendran, J. The efficacy of ice recrystallization inhibitors in rat lung cryopreservation using a low-cost technique for ex vivo subnormothermic lung perfusion. Cryobiology 97: 93-100 (2020).
  1. Cryoprotectant-dependent control of intracellular ice recrystallization in hepatocytes using small molecule carbohydrate inhibitors.
    William, N. and Acker, J.P. Cryoprotectant-dependent control of intracellular ice recrystallization in hepatocytes using small molecule carbohydrate inhibitors Cryobiology 97: 123-130 (2020).
  1. Characterizing the ability of an ice recrystallization inhibitor to improve platelet cryopreservation.
    Waters, L., Ben, R., Acker, J.P., Padula, M.P., Marks, D.C. and Johnson, L. Characterizing the ability of an ice recrystallization inhibitor to improve platelet cryopreservation. Cryobiology 96: 152-158 (2020)
  1. Control of ice recrystallization in liver tissues using small molecule carbohydrate derivatives.
    William, N. and Acker, J.P. Control of ice recrystallization in liver tissues using small molecule carbohydrate derivatives. Cryobiology 97: 250-253 (2020).
  1. Inhibition of ice recrystallization during cryopreservation of cord blood grafts improves platelet engraftment.
    Jahan, S., Adam, M.K., Manesia, J.K., Doxtator, E., Ben, R.N. and Pineault, N. Inhibition of ice recrystallization during cryopreservation of cord blood grafts improves platelet engraftment. Transfusion 60: 769-778 (2020).
  1. Modulating intracellular ice growth with cell permeating small molecule ice recrystallization inhibitors.
    Poisson, J.S., Acker, J.P., Briard, J.G., Meyer, J.E. and Ben, R.N. Modulating intracellular ice growth with cell permeating small molecule ice recrystallization inhibitors. Langmuir 35 (23): 7452-7458 (2019).
  1. Hydroxyethyl starch supplemented with ice recrystallization inhibitors greatly improves cryopreservation of human red blood cells.
    Poisson, J., Briard, J., Turner, T.R., Acker, J.P. and Ben, R. Hydroxyethyl starch supplemented with ice recrystallization inhibitors greatly improves cryopreservation of human red blood cells. BioProcessing Journal 15 (4): 16-21 (2017).
  1. O-Aryl-glycoside ice recrystallization inhibitors as novel cryo-protectants – A structure-function study.
    Capicciotti, C., Mancini, R., Turner, T.R., Koyama, T., Alteen, M., Doshi, M., Inada, T., Acker, J.P. and Ben, R. O-Aryl-glycoside ice recrystallization inhibitors as novel cryo-protectants – A structure-function study. ACS Omega 1: 656-662 (2016).
  1. Small molecule ice recrystallization inhibitors mitigate cellular damage during freezing, transient warming and thawing.
    Briard, J.G., Poisson, J.S., Turner, T.R., Acker, J.P. and Ben, R.N. Small molecule ice recrystallization inhibitors mitigate cellular damage during freezing, transient warming and thawing. Nature Scientific Reports 6: 23619 (2016).
  1. QSAR accelerated discovery of potent ice recrystallization inhibitors.
    Briard, J.G., Fernandez, M., De Luna, P., Woo, T.K. and Ben, R.N. QSAR accelerated discovery of potent ice recrystallization inhibitors. Nature Scientific Reports. 6: 26403 (2016).
  1. Small-molecule ice recrystallization inhibitors improve the post-thaw function of hematopoietic stem and progenitor cells.
    Briard, J.G., Jahan, S., Chandran, P., Allan, D., Pineault, N. and Ben, R.N. Small-molecule ice recrystallization inhibitors improve the post-thaw function of hematopoietic stem and progenitor cells. ACS Omega 1 (5): 1010-1018 (2016).
  1. Small ice recrystallization inhibitors enable freezing of human red blood cells with reduced glycerol concentrations.
    Capicciotti, C.J., Tchir, J.D.R., Turner, T., Mancini, R.S., Acker, J.P. and Ben, R.N. Small ice recrystallization inhibitors enable freezing of human red blood cells with reduced glycerol concentrations. Nature Scientific Reports 5: 9692 (2015).
  1. Inhibiting gas hydrate formation using small molecule ice recrystallization inhibitors.
    Tonelli, D., Capicciotti, C.J., Doshi, M. and Ben, R.N. Inhibiting gas hydrate formation using small molecule ice recrystallization inhibitors. RSC Advances 5: 21728 (2015).
  1. Quantitative analysis of the efficacy and potency of novel small molecule ice recrystallization inhibitors.
    Abraham, S., Keillor, K., Capicciotti, C.J., Perley-Robertson, E., Keillor, J.W. and Ben, R.N. Quantitative analysis of the efficacy and potency of novel small molecule ice recrystallization inhibitors. Crystal Growth & Design 15: 5034-5039 (2015).
  1. Designing ice recrystallization inhibitors: From antifreeze (glyco)proteins to small molecules.
    Balcerzak, A.K., Capicciotti, C.J., Briard, J.G. and Ben, R.N. Designing ice recrystallization inhibitors: From antifreeze (glyco)proteins to small molecules. RSC Advances 4: 42682 (2014).
  1. Assessing the ability of a short-fluorinated antifreeze glycopeptide and a fluorinated carbohydrate derivative to inhibit ice recrystallization.
    Chaytor, J.L. and Ben, R.N. Assessing the ability of a short-fluorinated antifreeze glycopeptide and a fluorinated carbohydrate derivative to inhibit ice recrystallization. Bioorganic & Medicinal Chemistry Letters 20 (17): 5251-5254 (2010).

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